This page contains descriptions and examples to extract GWAS-implicated gene expression data and project them to cortical and subcortical surfaces. In the following tutorial, we will use epilepsy-related genes (more specifically, genes related to hippocampal sclerosis) as an example, but feel free to replace epilepsy with any other disorder listed below.
Extract disease-related genes¶
* 📸 indicates disease-related genes used in the code snippets.
Pre-defined gene sets are obtained from individual studies and are liable to be changed. We welcome any suggestions you may have on defining proper disease-related gene sets and are happy to expand this function to include other interesting disorders. Get in touch with us here.
Prerequisites ↪ Fetch gene expression data
Visualize disease-related gene expression maps¶
Following up on the above example, we provide a brief example to project gene expression maps to the surface. Once again, we use genes related to hippocampal sclerosis as an example.
Prerequisites ↪ Fetch gene expression data ↪ Extract disease-related gene data